Researchers find longer genes are linked with cause of ageing

Ageing is a natural part of life but what causes our bodies to age remains a question. A recent research reached the same conclusion, long genes.

The scientists describe their results and how they lead to existing information about ageing.

The co-corresponding author of the study Thomas Stoeger in the study noted that long genes that become less active with age may be the central reason for ageing in our bodies. As per their findings, the field is finding a single phenomenon that connects most existing information about ageing and makes this idea measurable. The groups are the first to conclude that most aspects of biological ageing relate to gene length.

Factors leading to accelerated ageing

According to the researchers, conditions or factors known to accelerate ageing reduce the activity of long genes. These conditions include oxidative stress and UV irradiation. The conditions known to slow ageing increase the activity of long genes such as caloric restriction. In fact, the very short or long genes include cellular energy, protein synthesis and the spread of neural signals.

The stimulation of genes is one of the most central processes of life and the four studies of the research explain the reason why the activity of long genes in certain changes in ageing. Along with the other changes the findings of the studies have found that occurs in patients with Alzheimer’s disease, an age-related disease.

As per the findings the causes of neurodegenerative diseases like Alzheimer’s disease. As per the hypothesis of the researchers, the decreased activity of long gene cells fails to produce sufficient biomaterials to properly maintain neural function, this happens because the genes with neural function are unusually long.

What triggers ageing?

The trigger of ageing is a physical condition that is related to the length of the genes and not to the specific genes included or the function of those genes, the researchers noted. The original findings were based on a mixture of molecular data from humans, mice, rats, killfish and C elegans. As per the earlier research the ways to identify the specific genes responsible for ageing.