Scientists discover potential new drug for Ebola virus

Scientists have made a discovery that could potentially help in the treatment of Ebola, a deadly virus responsible for devastating outbreaks, particularly in sub-Saharan Africa.

This discovery centres around identifying a specific target within the virus that could be singled out by drugs to halt its spread in the human body.

Ebola is a highly virulent (spreads quickly) virus known to cause severe illness in humans, with symptoms ranging from flu-like manifestations to more severe complications such as bleeding and neurological issues.

Despite efforts to contain its spread and treat those infected, Ebola continues to pose a significant threat to public health.

Published in the journal PLOS Biology, the findings of this study offer hope in the fight against Ebola and pave the way for further research.

The study focused on understanding how Ebola interacts with a protein called ubiquitin, which plays a crucial role in various cellular processes within the body.

Ebola is a highly virulent virus known to cause severe illness in humans. (Photo: Getty Images)
By employing a combination of experimental methods and advanced computer modelling techniques, the researchers unravelled the intricate dynamics of the interaction between a viral protein known as VP35 and ubiquitin chains present in human cells.

Through their research, the scientists not only elucidated the mechanism by which Ebola exploits ubiquitin but also identified potential chemical compounds capable of disrupting this interaction.

These compounds hold promise as future candidates for the development of targeted therapies that can help slow down viral replication and curb the progression of the disease.

By highlighting the molecular intricacies of the virus and unveiling a potential vulnerability that can be exploited for therapeutic purposes, this research marks a crucial step forward in the ongoing battle against Ebola.

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